Nano&Bio Sensor Laboratory
Research
Nano&Bio Sensor Laboratory
Research
Research
Carbon nanotubes (CNTs) and graphene have attracted increasing interest due to their excellent electrical, mechanical, thermal, and optical properties. The outstanding properties of CNTs and graphene have established conductive films as a new class of optically transparent and electrically conduction materials that can be used in applications such as field emission displays, sensors, thin film transistors, and transparent electrodes for optoelectronic devices. Successful implementation of the films for various applications requires high quality and high resolution patterning at defined positions, with large-scale control of location and orientation. In our research group, we have developed novel methods for micro-patterning of CNTs, graphene, and silver nanowire on flexible substrates by oxygen plasma, vacuum filtration, and chemical etching techniques
Micro-patterning of Carbon Nanotubes by Oxygen Plasma Treatment
Graphene Electrode on Flexible PET Substrate (Left) and CNT Electrode on Paper Substrate (Right)
Microelectromechanical systems (MEMS) have provided a unique opportunity to fabricate miniature biomedical devices for a variety of applications. Miniaturization of analytical devices offers many advantages such as short reaction time, safe handling, low consumption of reactants, and automation. Microfabrication techniques also permit biosensors to be constructed as arrays and various components like reactor and detector to be integrated into the same devices. We focus on the development of microbiochip for high-throughput screening using photolithography, soft lithography, and microimprinting
Electrochemical Plastic-based Microfluidic Chips
PDMS Microfluidic Chip (Left) and Paper-based Lateral Flow Assay Chip (Right)
During the past few decades, nanozymes, a class of nanomaterials that has enzyme-like catalytic activities, have been explored as a next generation of enzyme alternatives. Indeed, compared to natural enzymes, previous studies have shown that these nanomaterial-based artificial enzymes exhibit powerful benefits, such as low production cost, simple preparation process, ease of use, high stability without denaturation in ambient conditions, and predisposition for catalytic activity, leading to diverse practical applications, including biosensors, electrochemical analysis, colorimetric diagnosis, and therapeutics. The structure and composition of the artificial enzymes are important for enhancing the catalytic properties. Therefore, nanozymes have been developed with various structures and different compositions of metal nanoparticles, metal-organic framework, carbon based-materials, and hybrid nanostructures. In our research group, nanozymes have been synthesized by a variety of techniques, and the fabricated nanozymes are used as artificial enzymes for the development of electrochemical (bio)chemical sensors.
Nanozymes as Artificial Enzymes for Diagnosis
Nanozymes for In vitro/In vivo Cancer Therapy